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PERIODONTOPATHIC BACTERIA IN SUBGINGIVAL PLAQUE OF NORMAL AND HANDICAPPED PERSON

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Abstract

Á¤»óÀΰú Á¤½ÅÁöüÀÎ ±×¸®°í ´Ù¿îÁõÈıº ȯÀÚ¿¡¼­ Ä¡ÁÖ»óÅ ¹× Ä¡ÁÖÁúȯ ¿øÀαÕÀÇ ÃâÇöÀ²À» ºñ±³ Æò°¡ÇÏ°íÀÚ Á¤»ó Çлý 65¸í°ú Á¤½ÅÁöü¸¦ °¡Áø Çлý 34¸í, ´Ù¿îÁõÈıºÀ» °¡Áø Çлý 28¸í, ÃÑ 127¸íÀ» Á¶»ç´ë»óÀ¸·Î Ä¡ÅÂÁö¼ö¿Í Ä¡ÀºÁö¼ö¸¦ ÃøÁ¤ÇÏ°í Ä¡Àº¿¬ÇÏ Ä¡Å¿¡ Á¸ÀçÇÏ´Â Porphyromonas gingivalis, Tannerella forsythia(B. forsythus), Treponema denticola, Fusobacterium nucleatum, Actinobacillus actinomyce temcomitans ±ÕÀ» ÁßÇÕÈ¿¼Ò¿¬¼â¹ÝÀÀÀ» ÀÌ¿ëÇÏ¿© °Ë»çÇÏ°í ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù. 1. Ä¡ÅÂÁö¼ö¿Í Ä¡ÀºÁö¼ö´Â Á¤½ÅÁöüÀαº°ú ´Ù¿îÁõÈıº ȯÀÚ±º¿¡¼­ Á¤»óÀ১¸´Ù ³ô¾Ò´Ù.
2. Á¤½ÅÁöüÀαº°ú ´Ù¿îÁõÈıº ȯÀÚ±ºÀº Á¤»óÀ২¡ ºñÇØ Ä¡ÁÖÁúȯ ¿øÀαÕÀÇ ÃâÇöÀ²ÀÌ ³ô¾ÒÀ¸¸ç ƯÈ÷ P. gingivalis¿Í T. denticola. A. actinomycetemcomitans°¡ À¯ÀÇÇÑ Â÷À̸¦ º¸¿´´Ù. ´Ù¿îÁõÈıº ȯÀÚ±º°ú Á¤½ÅÁöüÀαºÀÇ ºñ±³½Ã Ä¡ÁÖÁúȯ ¿øÀαÕÀÇ ÃâÇöÀ²Àº À¯ÀÇÇÑ Â÷À̸¦ º¸ÀÌÁö ¾Ê¾Ò´Ù.
3. ¿¬·Éº° ºñ±³½Ã Á¤»óÀαºÀÇ P. gingivalis´Â 14¼¼À̻󱺿¡¼­ Å©°Ô Áõ°¡ÇÏ´Â ¾ç»óÀ» º¸¿´´Ù. Á¤½ÅÁöüÀαº°ú ´Ù¿îÁõÈıº ȯÀÚ±º¿¡¼­ P. gingivalis´Â Á¤»óÀ১¸´Ù Á¶±â¿¡ ´õ ³ôÀº ºñÀ²·Î ÃâÇöÇÏ¿´À¸¸ç ¿¬·ÉÀÇ Áõ°¡¿¡ µû¶ó Áõ°¡¾ç»óÀ» º¸¿´´Ù. T. denticola, A. actinomycetemcomitans´Â Á¤»óÀ১¸´Ù Á¤½ÅÁöüÀαº°ú ´Ù¿îÁõÈıº ȯÀÚ±º¿¡¼­ ¸ðµç ¿¬·É´ë¿¡¼­ ³ôÀº ºñÀ²À» º¸¿´´Ù.
4. Ä¡ÅÂÁö¼ö´Â T. denticola¿Í À¯ÀÇÇÑ °ü·Ã¼ºÀÌ ÀÖ¾úÀ¸¸ç, Ä¡ÀºÁö¼ö´Â T. denticola, A. actinomycetemcomitans¿Í ³ôÀº °ü·Ã¼ºÀ» º¸¿©ÁÖ¾ú´Ù.
ÀÌ»óÀÇ °á°ú¸¦ ¿ä¾àÇØ º¸¸é Á¤½ÅÁöüÀαº°ú ´Ù¿îÁõÈıº ȯÀÚ±ºÀº Á¤»óÀ১¸´Ù Ä¡ÅÂÁö¼ö, Ä¡ÀºÁö¼ö°¡ ´õ ³ô¾ÒÀ¸¸ç, P. gingivalis, T. denticola, A. actinomycetemcomitansÀÇ ÃâÇöÀ²¿¡¼­ À¯ÀÇÇÑ Â÷À̸¦ º¸¿´´Ù. ´Ù¿îÁõÈıº ȯÀÚ±º°ú Á¤½ÅÁöüÀαºÀº Ä¡ÁÖÁúȯ ¿øÀαÕÀÌ ¾î¸° ½Ã±âºÎÅÍ ¸Å¿ì ³ô°Ô ÃâÇöÇÏ¿´À¸¸ç, µÎ ±º°£¿¡´Â À¯ÀÇÇÒ ¸¸ÇÑ Â÷À̸¦ º¸ÀÌÁö ¾Ê¾Ò´Ù.

It is widely known that individuals with mental retardation (MR) and Down¡¯s syndrome (DS) often develop early onset periodontal diseases. In this study, the prevalence of periodontopathic bacteria in MR persons and DS patients was compared with normal persons. Plaque index and gingival index were measured. Five periodontopathic bacteria, Actinobacillus actinomycetemcomitans. Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum were surveyed in subgingival plaque samples by the polymerase chain reaction.
Results :
1. Plaque index and gingival index were higher in MR persons group and DS patients group than normal persons group (p<0.05).
2. The prevalence of periodontopathic bacteria in normal persons group were lower than that of MR persons group and DS. Significant differences were observed in the prevalence of P. gingivalis, T. denticola and A. actinomycetemcomitans(P<0.05).
3. Prevalence of P. gingivalis(5.9%) at age 8-10 was lower than other ages in normal persons group, and its prevalence increased with age Prevalence of P. gingivalis, T. denticola and A. actinomycetemcomitans at MR persons group and DS patients group were higher than those of same ages of normal persons group.
4. Plaque index was associated with T. denticola and gingival index was associated with T. denticola and A. actinomycetemcomitans(P<0.05).
These results suggested that plaque index, gingival index and prevalence of periodontopathic pathogens, especially P. gingivalis, T. denticola and A actinomycetemcomitans in DS patients group and MR persons group are higher than those of normal persons group.

Å°¿öµå

´Ù¿îÁõÈıº Á¤½ÅÁöüÀÎ;Ä¡ÁÖÁúȯ ¿øÀαÕ;ÁßÇÕÈ¿¼Ò¿¬¼â¹ÝÀÀ;Ä¡ÀºÁö¼ö;Ä¡ÅÂÁö¼ö
Down¡¯s syndrome;Mental retardation;Periodontopathic bacteria;Polymerase chain reaction;Gingival index;Plaque index

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